The primary outcome measure was in-hospital all-cause mortality secondary outcome measures were LOS and the number of comorbidities.Ī total of 39,323 inpatients were included in the final analysis. The MELD score on hospital admission was calculated retrospectively. From January 2012 through December 2013, all consecutive inpatients aged 18 years were eligible for the study patients with missing MELD parameters on hospital admission and/or treatments influencing the international normalized ratio, that is, novel oral anticoagulants and vitamin K antagonists, were excluded. We performed a retrospective observational study at a tertiary referral center. We therefore aimed to investigate a potential association of the MELD score with mortality, length of hospital stay (LOS), and disease burden in a general patient population. The laboratory-based model for end-stage liver disease (MELD) score reflects the function of the kidney, liver, and extrinsic coagulation pathway and might be used as a general prognostic tool for the assessment of patients.
Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website ( This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Supplemental digital content is available for this article. Supplemental Digital Content is available for this article. The authors report no conflicts of interest. Otherwise, the authors have no funding or conflicts of interest to disclose.Įxcerpts of the results were presented as poster at the « International Forum of Safety and Quality in Health Care » in London April 21-24th, 2015. This study was supported by the Gebert Rüf Foundation (grant GRS 030/09), Basel, Switzerland.
Hug, Department of Internal Medicine, Kantonsspital Luzern, Spitalstrasse, 6000 Luzern 16, Switzerland (e-mail: ).Ībbreviations: CI = confidence interval, HR = hazard ratio, ICD-10 = International Classification of Diseases (10th revision), INR = international normalized ratio, IRR = incidence rate ratio, LOS = length of hospital stay, MELD = model for end-stage liver disease.
ADivision of Infectious Diseases & Hospital EpidemiologyĭClinical Trial Unit, University Hospital Basel, BaselĮDepartment of Internal Medicine, Kantonsspital Luzern, Lucerne, Switzerland.Ĭorrespondence: Dr.